![]() ![]() Medicines 3:3Ībutaha N, Mashaly AM, Al-Mekhlafi FA, Farooq M, Al-Shami M, Wadaan MA (2015) Larvicidal activity of endophytic fungal extract of Cochliobolus spicifer (Pleosporales: Pleosporaceae) on Aedes caspius and Culex pipiens (Diptera: Culicidae). Civil Env Res 3:108–114Ībubakar MN, Majinda RR (2016) GC-MS analysis and preliminary antimicrobial activity of Albizia adianthifolia (Schumach) and Pterocarpus angolensis (DC). The granule formulations can be used as an effective biocontrol strategy against malaria-causing mosquitoes.Ībdulkarim A, Isa MT, Abdulsalam S, Muhammad AJ, Ameh AO (2013) Extraction and characterization of chitin and chitosan from mussel shell. The developed LL granule formulation exhibited high toxicity against Anopheles mosquitoes. Further, the SEM EDX (energy dispersive X-ray) studies revealed that the treated larvae have lower nitrogen content which is correlated to a lower level of chitin whereas the control ones has higher chitin content and healthy membranes. The findings from SEM and histopathology also substantiated the mortality effects. The developed formulation was found to be lethal against Anopheles culicifacies with an LC 50 value of 11.836 µg/mL. lecanii was also performed to screen the potential biomolecules present. The developed formulation was also subjected to an accelerated temperature study at 40 ☌ and was found to be stable for 3 months. Developed 4% LL granules have been characterized using the technique of Fourier transform infrared spectroscopy (FTIR) and scanning electron microscope (SEM). In the present paper, the entomopathogenic fungus, Lecanicillium lecanii (LL) was processed to make the granules. In this context, many such bioactive compounds originating from entomopathogenic microbes serve as an alternative strategy and environmentally benign tool for vector control. However excessive and non-judicious usage of such chemically derived insecticides has led to serious environmental and health issues owing to their biomagnification ability and increased toxicity towards non-target organisms. Mostly synthetic insecticides are usually applied as a primary control strategy to manage vector-borne diseases. Mosquitoes are infectious vectors for a wide range of pathogens and parasites thereby transmitting several diseases including malaria, dengue, Zika, Japanese encephalitis and chikungunya which pose a major public health concern. ![]()
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